Genetic Screening Lab team photo at CEMB

Research laboratory

Genetic Screening

The lab explores the genetic and epigenetic basis of complex diseases prevalent in Pakistan — asthma, lung cancer, COPD and congenital hypogonadotropic hypogonadism — to help personalise patient treatment.

Research with real-world impact

From laboratory discovery to practical solutions.

Research links genetic profiles to treatment response for complex, common diseases, and is developing cost-effective third-generation sequencing facilities to bring precision genomics to more researchers and clinicians.

Medical & precision genomicsComplex disease geneticsThird-generation sequencing
2
faculty investigators
7
research scholars
5
funded research projects
4
notable outcomes

Research programme

Our research programme.

The programme connects discovery, laboratory validation and the development of tools and products for real-world use.

  1. 01

    Complex disease genetics

    Genetic and epigenetic association studies of asthma, lung cancer, COPD and congenital hypogonadotropic hypogonadism.

  2. 02

    Precision genomics for treatment

    Linking patient genetic profiles to treatment plans to improve outcomes and reduce adverse reactions.

  3. 03

    Sequencing facility development

    Developing cost-effective protocols for third-generation sequencing for researchers and clinicians.

Translation & outcomes

Research built to leave the laboratory.

Notable outcomes, products, services and intellectual property from the group.

01

Collaborating partner in a Swiss National Science Foundation project on genetic variants linked to Congenital Hypogonadotrophic Hypogonadism in the Pakistani population

02

Genotypic categorisation of patients who respond better to Vitamin D supplements for suppressing COPD symptoms, with Fatima Memorial Hospital Lahore

03

Identified genetic variants predisposing the local population to asthma, COPD and lung cancer, published in the Journal of Asthma, Clinical Respiratory Journal and CHEST

04

18 students have completed their MPhil from this lab, with 3 PhD and 2 MPhil students currently enrolled

Research group

Faculty leading the programme.

Meet the investigators who lead the laboratory’s research.

Research students

The questions shaping tomorrow’s science.

2 PhD scholars4 MPhil scholars1 Other researchers

PhD research scholars 2

Ali Raza

PhD Research Scholar

Aroosa Ijaz

PhD Research Scholar

MPhil research scholars 4

Sahar Yousaf

MPhil Research Scholar

Hadeena Musarrat

MPhil Research Scholar

Amna Sadaf

MPhil Research Scholar

Sumaira

MPhil Research Scholar

Research team 1

Asad Shah

Research Scholar

Research funding

A sustained pipeline of funded research.

Competitive public funding and partnerships support the laboratory’s projects.

Active projects

Cost-effective BRCA1/2 screening for early cancer detectionApproved by HEC-Pakistan Academy of Sciences, 2026 · Rs 8.63 million
Genetic basis of congenital pituitary disorders in Pakistan: PROP1 variants and population riskPunjab University · 2025–2026 · Rs 0.3 million
Genotypic categorisation of COPD patients by Vitamin D receptor SNP variantsHEC NRPU, Ref. 20-15440/NRPU/R&D/HEC/2021-2020 · Rs 7.8 million
Genetic variants associated with Congenital Hypogonadotropic Hypogonadism in the Pakistani populationSwiss National Science Foundation collaboration

Completed projects

Association of candidate SNPs on chromosome 14 with inherited emphysema in the local populationHEC NRPU-8460 · Rs 1.87 million

Collaborate with the lab

Bring a research challenge. Build the next solution.

Contact the group lead